The NPI must be used in lieu of legacy provider identifiers in the HIPAA standards transactions. This means that the numbers do not carry other information about healthcare providers, such as the state in which they live or their medical specialty. The NPI is a 10-position, intelligence-free numeric identifier (10-digit number). What is a NPI Number? : The National Provider Identifier (NPI) is a unique identification number for covered health care providers. Often these therapies require specialized delivery and administration. physician offices, ER, Urgent Care Centers, Rural Health Facilities, etc.)Ī pharmacy that dispenses generally low volume and high cost medicinal preparations to patients who are undergoing intensive therapies for illnesses that are generally chronic, complex and potentially life threatening. Mail order pharmacies are licensed as a Mail Order Pharmacy in the state where they are located and may also be licensed or registered as nonresident pharmacies in other states.Ī site other than a pharmacy that dispenses medicinal preparations under the supervision of a physician to patients for self-administration. Mail order pharmacies counsel patients and caregivers (sometimes independent of the dispensing process) through telephone or email contact and provide other professional services associated with pharmaceutical care appropriate to the setting. It meets any licensing or certification standards set forth by the jurisdiction where it is located.Ī pharmacy which uses common carriers to deliver the medications to patient or their caregivers. Provider Business Mailing Address Details:Ī facility used by pharmacists for the compounding and dispensing of medicinal preparations and other associated professional and administrative services.Ī pharmacy is a facility whose primary function is to store, prepare and legally dispense prescription drugs under the professional supervision of a licensed pharmacist. The mailing address for Ascension Rx 1402 is 4205 Belfort Rd Ste 1003,, Jacksonville, Florida - 32216-5876 (mailing address contact number - 90). The current location address for Ascension Rx 1402 is 4201 Belfort Rd Ste G361,, Jacksonville, Florida and the contact number is 90 and fax number is 90. The NPI Number for Ascension Rx 1402 is 1366783441. Carboplatin is also used in a variety of malignancies such as ovarian cancer, bladder cancer, metastatic breast cancer, cervical cancer, esophageal cancer, head and neck cancer, lymphoma, lung cancer, unknown primary adenocarcinoma and testicular cancer.Ascension Rx 1402 (SETON PHARMACY INC.) is a Community/Retail Pharmacy in Jacksonville, Florida. Carboplatin is FDA approved for the initial or palliative (previously treated with cisplatin) treatment of advanced ovarian tumors when combined with other approved chemotherapy agents. Since carboplatin is less nephrotoxic, neurotoxic and emetogenic than cisplatin, it can be an ideal agent for dose-intensive and/or combination chemotherapies.Ĭarboplatin was introduced in 1981 as a favorable alternative to cisplatin for the treatment of many solid tumors. An AUC of 4 to 7 has manageable myelosuppressive effects with desirable efficacy against malignant cancers. Carboplatin is much less toxic than cisplatin, but its dose-limiting toxicity is myelosuppression (especially thrombocytopenia). The exposure to carboplatin is well characterized by its AUC, which is associated with its antineoplastic activity as well as toxicity. It is primarily excreted by the kidneys via tubular filtration. Carboplatin has minimal hepatic metabolism rather, it undergoes spontaneous hydrolysis to become active. Unlike cisplatin, it has minimal protein binding and distributes well into ascites, pleural fluid, liver, kidney, skin and tumor tissues. It causes cell cycle arrest in the G2-phase then induces cellular apoptosis.Ĭarboplatin is administered primarily through IV infusion. Carboplatin is a cell cycle non-specific agent with increased activity during the S-phase. This irreversible binding results in the inhibition of DNA replication. Once inside the cell, carboplatin is hydroxylated by water to form the active compound, then it covalently binds to DNA at two sites, forming interstrand and intrastrand cross-links. Carboplatin, a second generation analog of cisplatin, has cytotoxic activity similar to cisplatin. Carboplatin belongs to the class of platinum-containing antineoplastic agents, which also includes cisplatin and oxaliplatin.
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